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Article

Steering of carcinoma progression by the YIN/YANG interaction of STAT1/STAT3

1 Jan 2017

Abstract excerpt

STAT1/STAT3 transcription factors are important regulators for development of normal, infected or inflammed cells. They are also critically involved in the progression of various malignant tumours, including epithelial-derived carcinomas. Here, we focus on colorectal cancer (CRC) insights for STAT1/3, where controversial functions for STAT3 were reported. For a long time STAT3 has been regarded as a driver of...

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Identifiers

PMID: 28154246
DOI: 10.5582/bst.2016.01250

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