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Article

GALNT2 effect on HDL-cholesterol and triglycerides levels in humans: Evidence of pleiotropy?

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Apr 2017

Di Paola R, Marucci A, Trischitta V

Abstract excerpt

A wide range of studies both in humans and animal models point GALNT2 as a shaper of serum HDL-C and TG levels. Available data in humans indicate that, while under conditions of extreme GALNT2 loss-of-function HDL-C is the main target, a fine-tuning of GALNT2 changes is mostly associated with TG levels. Understanding whether different degrees of GALNT2 change do modulate different serum lipid fractions and, if...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Genetic Pleiotropy

Share to N-Acetylgalactosaminyltransferases

Share to Polypeptide N-acetylgalactosaminyltransferase

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Source

Identifiers

PMID: 28153384
DOI: 10.1016/j.numecd.2016.11.006

Genes

GALNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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