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Article

LAG-3 Protein Expression in Non-Small Cell Lung Cancer and Its Relationship with PD-1/PD-L1 and Tumor-Infiltrating Lymphocytes.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2017

He Yayi, Yu Hui, Rozeboom Leslie, Rivard Christopher J, Ellison Kim, Dziadziuszko Rafal, Suda Kenichi, Ren Shengxiang, Wu Chunyan, Hou Likun, Zhou Caicun, Hirsch Fred R

Abstract excerpt

INTRODUCTION: Immunotherapy targeting the programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) checkpoint has shown promising efficacy in patients with NSCLC. Lymphocyte activating 3 gene (LAG-3) is another important checkpoint, and its role in NSCLC is still not clear. In this study we investigated lymphocyte activing 3 (LAG-3) protein expression; its correlation with PD-1, PD-L1, and tumor-inﬁltrating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28132868
DOI: 10.1016/j.jtho.2017.01.019

Genes

ALK
EGFR
KRAS
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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