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Article

The Arabidopsis ceramidase AtACER functions in disease resistance and salt tolerance.

The Plant journal : for cell and molecular biology - 1 Mar 2015

Wu Jian-Xin, Li Jian, Liu Zhe, Yin Jian, Chang Zhen-Yi, Rong Chan, Wu Jia-Li, Bi Fang-Cheng, Yao Nan

Abstract excerpt

Ceramidases hydrolyze ceramide into sphingosine and fatty acids. In mammals, ceramidases function as key regulators of sphingolipid homeostasis, but little is known about their roles in plants. Here we characterize the Arabidopsis ceramidase AtACER, a homolog of human alkaline ceramidases. The acer-1 T-DNA insertion mutant has pleiotropic phenotypes, including reduction of leaf size, dwarfing and an irregular wax...

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PMID: 25619405
DOI: 10.1111/tpj.12769

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