Article
Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene.
Domestic animal endocrinology - 1 Apr 2017
Scudder C J, Niessen S J, Catchpole B, Fowkes R C, Church D B, Forcada Y
Abstract excerpt
Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene. Feline acromegaly has similarities to human acromegalic families with AIP mutations. The aim of this study was to sequence the feline AIP gene, identify sequence variants and compare the AIP gene sequence...
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