Article
Clinical phenotypes and the biological parameters of Congolese patients suffering from sickle cell anemia: A first report from Central Africa.
Journal of clinical laboratory analysis - 1 Nov 2017
Mikobi Tite M, Lukusa Tshilobo Prosper, Aloni Michel N, Akilimali Pierre Z, Mvumbi-Lelo Georges, Mbuyi-Muamba Jean Marie
Abstract excerpt
BACKGROUND: The influence of phenotype on the clinical course and laboratory features of sickle cell anemia (SCA) is rarely described in sub-Saharan Africa. METHODS: A cross-sectional study was conducted in Kinshasa. A clinical phenotype score was built up. The following definitions were applied: asymptomatic clinical phenotype (ACP; score≤5), moderate clinical phenotype (MCP; score between 6 and 15), and severe...
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