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Article

Establishment of DNA methylation patterns of the Fibrillin1 (FBN1) gene in porcine embryos and tissues.

The Journal of reproduction and development - 21 Apr 2017

Arai Yoshikazu, Umeyama Kazuhiro, Takeuchi Kenta, Okazaki Natsumi, Hichiwa Naomi, Yashima Sayaka, Nakano Kazuaki, Nagashima Hiroshi, Ohgane Jun

Abstract excerpt

DNA methylation in transcriptional regulatory regions is crucial for gene expression. The DNA methylation status of the edges of CpG islands, called CpG island shore, is involved in tissue/cell-type-specific gene expression. Haploinsufficiency diseases are caused by inheritance of one mutated null allele and are classified as autosomal dominant. However, in the same pedigree, phenotypic variances are observed...

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Identifiers

PMID: 28111381
DOI: 10.1262/jrd.2016-158
PMCID: PMC5401809

Genes

FBN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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