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Article

CASPASE-8 gene polymorphisms (rs13416436 and rs2037815) are not associated with preeclampsia development in Brazilian women.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Feb 2018

Orlando Ivanir Celso, Tanaka Sarah Cristina Sato Vaz, Balarin Marly Aparecida Spadotto, da Silva Sueli Riul, Pissetti Cristina Wide

Abstract excerpt

BACKGROUND: Preeclampsia is responsible for considerable mortality and morbidity of mother and sibling. The etiology of preeclampsia is still unknown. Family studies indicate the involvement of genes located on chromosome 2 in preeclampsia development. Considering the importance of apoptosis and chromosome 2, one promising candidate for the study of the genetic cause of this syndrome is the CASPASE-8 gene, which...

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Identifiers

PMID: 28110598
DOI: 10.1080/14767058.2017.1285882

Genes

CASP8

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