Article
Role of the 12q24.12 locus in the onset of preeclampsia: an Italian case-control study.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Aug 2012
Di Gaetano Cornelia, Marozio Luca, Voglino Floriana, Guarrera Simonetta, Tancredi Annalisa, Gibbone Elena, Benedetto Chiara, Gasparini Mauro, Piazza Alberto, Matullo Giuseppe
Abstract excerpt
OBJECTIVE: The 12q24.12 locus has been reported to be involved in the control of many traits and also in severe diseases such as cardiovascular disease, hypertension and some immune-related disease. To our knowledge, no study has been published so far investigating the role of this locus in the pathogenesis of preeclampsia (PE). METHODS: We genotyped four single nucleotide polymorphisms (SNPs) in 12q24.12 locus...
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