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Article

The road to linearity: why linearity at low doses became the basis for carcinogen risk assessment.

Archives of toxicology - 1 Mar 2009

Calabrese Edward J

Abstract excerpt

This article assesses the historical foundations of how linearity at low dose became accepted by the scientific/regulatory communities. While the threshold model was used in the 1920s/1930s in establishing radiation health standards, its foundations were challenged by the genetics community who a...

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PMID: 19247635
DOI: 10.1007/s00204-009-0412-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19247635-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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