Article
A receptor and neuron that activate a circuit limiting sucrose consumption.
eLife - 23 Mar 2017
Joseph Ryan M, Sun Jennifer S, Tam Edric, Carlson John R
Abstract excerpt
The neural control of sugar consumption is critical for normal metabolism. In contrast to sugar-sensing taste neurons that promote consumption, we identify a taste neuron that limits sucrose consumption in Drosophila. Silencing of the neuron increases sucrose feeding; optogenetic activation decreases it. The feeding inhibition depends on the IR60b receptor, as shown by behavioral analysis and Ca2+ imaging of an...
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