Article
Assessment of autoantibodies to interferon-ω in patients with autoimmune polyendocrine syndrome type 1: using a new immunoprecipitation assay.
Clinical chemistry and laboratory medicine - 27 Jun 2017
Larosa Maria Del Pilar, Mackenzie Rachel, Burne Peter, Garelli Silvia, Barollo Susi, Masiero Stefano, Rubin Beatrice, Chen Shu, Furmaniak Jadwiga, Betterle Corrado, Smith Bernard Rees
Abstract excerpt
BACKGROUND: Measurements of autoantibodies to interferon-ω (IFN-ω) in patients with autoimmune polyglandular syndrome type 1 (APS-1) were performed using a new immunoprecipitation assay (IPA) based on 125I-labeled IFN-ω. METHODS: We have developed and validated a new IPA based on 125I-labeled IFN-ω. Sera from 78 patients (aged 3-78 years) with clinically diagnosed APS-1, 35 first degree relatives, 323 patients...
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