Article
Risk Factors for Disseminated Coccidioidomycosis, United States.
Emerging infectious diseases - 1 Feb 2017
Odio Camila D, Marciano Beatriz E, Galgiani John N, Holland Steven M
Abstract excerpt
Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.
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