Article
High-Saturated-Fat Diet Increases Circulating Angiotensin-Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient-Dependent Increases of Blood Pressure.
Journal of the American Heart Association - 17 Jan 2017
Schüler Rita, Osterhoff Martin A, Frahnow Turid, Seltmann Anne-Cathrin, Busjahn Andreas, Kabisch Stefan, Xu Li, Mosig Alexander S, Spranger Joachim, Möhlig Matthias, Hornemann Silke, Kruse Michael, Pfeiffer Andreas F H
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme (ACE) plays a major role in blood pressure regulation and cardiovascular homeostasis. Contrary to the assumption that ACE levels are stable, circulating ACE has been shown to be altered in obesity and weight loss. We sought to examine effects of a high-saturated-fat (HF) diet on ACE within the NUtriGenomic Analysis in Twins (NUGAT) study. METHODS AND RESULTS: Forty-six...
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