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Article

Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster.

BMC genomics - 14 Jan 2017

Michalak Pawel, Kang Lin, Sarup Pernille M, Schou Mads F, Loeschcke Volker

Abstract excerpt

BACKGROUND: Evolutionary theory predicts that antagonistically selected alleles, such as those with divergent pleiotropic effects in early and late life, may often reach intermediate population frequencies due to balancing selection, an elusive process when sought out empirically. Alternatively, genetic diversity may increase as a result of positive frequency-dependent selection and genetic purging in...

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Identifiers

PMID: 28088192
DOI: 10.1186/s12864-017-3485-0
PMCID: PMC5237518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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