Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNAs and tRNA-derived fragments predict the transformation of myelodysplastic syndromes to acute myeloid leukemia.

Leukemia & lymphoma - 1 Sept 2017

Guo Yan, Strickland Stephen A, Mohan Sanjay, Li Shaoying, Bosompem Amma, Vickers Kasey C, Zhao Shilin, Sheng Quanhu, Kim Annette S

Abstract excerpt

Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders of the elderly that carry an increased risk of progression to acute myeloid leukemia (AML). Since small non-coding RNAs (sRNAs), including microRNA (miRNAs), act as regulators of cellular differentiation, we hypothesized that changes to sRNAs might be implicated in the progression of MDS to AML. We conducted sRNA sequencing on three sets of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Bone Marrow

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Gene Expression Profiling

Share to Leukemia, Myeloid, Acute

Share to MicroRNAs

Share to Myelodysplastic Syndromes

Share to RNA, Transfer

Source

Open in PubMed Open full text

Identifiers

PMID: 28084850
DOI: 10.1080/10428194.2016.1272680
PMCID: PMC5505168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNAs and tRNA-derived fragments predict the transformation of myelodysplastic syndromes to acute myeloid leukemia.PMID 28084850Read ↗

Hematopoiesis-related microRNA expression in myelodysplastic syndromesSemantic proximity Read ↗

MicroRNAs in the Myelodysplastic SyndromeSemantic proximity Read ↗

Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromesSemantic proximity Read ↗

Integrative analysis of next generation sequencing for small non-coding RNAs and transcriptional regulation in Myelodysplastic SyndromesSemantic proximity Read ↗

Micro<scp>RNA</scp>s in myeloid malignanciesSemantic proximity Read ↗

Molecular mechanisms of the progression of myelodysplastic syndrome to secondary acute myeloid leukaemia and implication for therapySemantic proximity Read ↗

Circulating Small Noncoding RNAs Have Specific Expression Patterns in Plasma and Extracellular Vesicles in Myelodysplastic Syndromes and Are Predictive of Patient Outcome.Semantic proximity Read ↗

Epigenetic alterations and microRNAsSemantic proximity Read ↗

The role of microRNA in myelodysplastic syndromes: beyond DNA methylation and histone modification.Semantic proximity Read ↗

Epigenetic Regulation in Myelodysplastic Syndrome as A Consequence of A MicroRNA Dysregulation.Semantic proximity Read ↗

Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations.Semantic proximity Read ↗

Identification of a risk dependent microRNA expression signature in myelodysplastic syndromesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.