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Article

Identification of a risk dependent microRNA expression signature in myelodysplastic syndromes

21 Feb 2011

Abstract excerpt

The myelodysplastic syndromes (MDS) display both haematological and biological heterogeneity with variable leukaemia potential. MicroRNAs play an important role in tumour suppression and the regulation of self-renewal and differentiation of haematopoietic progenitors. Using a microarray platform, we evaluated microRNA expression from 44 patients with MDS and 17 normal controls. We identified a thirteen microRNA...

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PMID: 21332710
DOI: 10.1111/j.1365-2141.2011.08581.x

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