Article
Management of direct antiviral agent failures.
Clinical and molecular hepatology - 1 Dec 2016
Buti María, Esteban Rafael
Abstract excerpt
The current standard of care for patients with chronic hepatitis C virus (HCV) infection is a combination of direct-acting antiviral agents (DAAs). Most HCV patients treated with these drugs achieve viral elimination, but 1% to 15% fail to attain this objective. Treatment failures are usually related to relapse, and less often to on-treatment viral breakthrough. HCV drug resistant associated substitutions are...
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