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Article

Loss of Function of Evc2 in Dental Mesenchyme Leads to Hypomorphic Enamel.

Journal of dental research - 1 Apr 2017

Zhang H, Takeda H, Tsuji T, Kamiya N, Kunieda T, Mochida Y, Mishina Y

Abstract excerpt

Ellis-van Creveld (EvC) syndrome is an autosomal-recessive skeletal dysplasia, characterized by short stature and postaxial polydactyly. A series of dental abnormalities, including hypomorphic enamel formation, has been reported in patients with EvC. Despite previous studies that attempted to uncover the mechanism leading to abnormal tooth development, little is known regarding how hypomorphic enamel is formed in...

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Source

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Identifiers

PMID: 28081373
DOI: 10.1177/0022034516683674
PMCID: PMC5384488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Loss of Function of Evc2 in Dental Mesenchyme Leads to Hypomorphic Enamel.PMID 28081373Read ↗

The Role of Ellis-Van Creveld 2(EVC2) in Mice During Cranial Bone Development.Semantic proximity Read ↗

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