Article
Identification and characterization of HPV-independent cervical cancers.
Oncotarget - 21 Feb 2017
Banister Carolyn E, Liu Changlong, Pirisi Lucia, Creek Kim E, Buckhaults Phillip J
Abstract excerpt
BACKGROUND: Human papillomavirus (HPV) initiates cervical cancer, and continuous expression of HPV oncogenes E6 and E7 is thought to be necessary to maintain malignant growth. Current therapies target proliferating cells, rather than specific pathways, and most experimental therapies specifically target E6/E7. We investigated the presence and expression of HPV in cervical cancer, to correlate HPV oncogene...
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