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Article

Correlation between BRAF V600E mutation and clinicopathological features in pediatric papillary thyroid carcinoma.

Science China. Life sciences - 1 Jul 2017

Geng Jiangqiao, Wang Huanmin, Liu Yuanhu, Tai Jun, Jin Yaqiong, Zhang Jie, He Lejian, Fu Libing, Qin Hong, Song Yingluan, Su Jinzhu, Zhang Aiying, Wen Xin, Guo Yongli, Ni Xin

Abstract excerpt

In adults, the presence of the BRAF V600E mutation in papillary thyroid cancer (PTC) has been demonstrated to be strongly associated with aggressive cancer-cell characteristics and poor patient prognosis. In contrast, the frequency of this mutation in pediatric PTC has undergone limited study, and the few available estimates range from 0 to 63%. Furthermore, the role of the BRAF V600E mutation in pediatric PTC is...

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Topics

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Share to Adolescent
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Mutation

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 28646474
DOI: 10.1007/s11427-017-9083-8

Genes

BRAF

Variants

Provenance

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