Article
The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells.
Scientific reports - 11 Jan 2017
D'Elios Mario Milco, Vallese Francesca, Capitani Nagaja, Benagiano Marisa, Bernardini Maria Lina, Rossi Mirko, Rossi Gian Paolo, Ferrari Mauro, Baldari Cosima Tatiana, Zanotti Giuseppe, de Bernard Marina, Codolo Gaia
Abstract excerpt
Recent studies have shown that certain specific microbial infections participate in atherosclerosis by inducing inflammation and immune reactions, but how the pathogens implicated in this pathology trigger the host responses remains unknown. In this study we show that Helicobacter cinaedi (Hc) is a human pathogen linked to atherosclerosis development since at least 27% of sera from atherosclerotic patients...
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