Article
Chemokine Ligand 5 (CCL5) Derived from Endothelial Colony-Forming Cells (ECFCs) Mediates Recruitment of Smooth Muscle Progenitor Cells (SPCs) toward Critical Vascular Locations in Moyamoya Disease.
PloS one - 1 Jan 2017
Phi Ji Hoon, Suzuki Naoko, Moon Youn Joo, Park Ae Kyung, Wang Kyu-Chang, Lee Ji Yeoun, Choi Seung-Ah, Chong Sangjoon, Shirane Reizo, Kim Seung-Ki
Abstract excerpt
The etiology and pathogenesis of moyamoya disease (MMD) are still obscure. Previous studies indicated that angiogenic chemokines may play an important role in the pathogenesis of the disease. Recently, it was discovered that peripheral blood-derived endothelial colony-forming cells (ECFCs) and smooth muscle progenitor cells (SPCs) have defective functions in MMD patients. Therefore, the interaction of ECFCs and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.