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A Novel and Conserved Plasmodium Sporozoite Membrane Protein SPELD is Required for Maturation of Exo-erythrocytic Forms.

Scientific reports - 9 Jan 2017

Al-Nihmi Faisal Mohammed Abdul, Kolli Surendra Kumar, Reddy Segireddy Rameswara, Mastan Babu S, Togiri Jyothi, Maruthi Mulaka, Gupta Roshni, Sijwali Puran Singh, Mishra Satish, Kumar Kota Arun

Abstract excerpt

Plasmodium sporozoites are the infective forms of malaria parasite to vertebrate host and undergo dramatic changes in their transcriptional repertoire during maturation in mosquito salivary glands. We report here the role of a novel and conserved Plasmodium berghei protein encoded by PBANKA_091090 in maturation of Exo-erythrocytic Forms (EEFs) and designate it as Sporozoite surface Protein Essential for Liver...

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PMID: 28067322
DOI: 10.1038/srep40407
PMCID: PMC5220379

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