Article
An evaluation of the evolution of the gene structure of dystroglycan.
BMC research notes - 3 Jan 2017
Brancaccio Andrea, Adams Josephine C
Abstract excerpt
BACKGROUND: Dystroglycan (DG) is an adhesion receptor complex composed of two non-covalently associated subunits, transcribed from a single gene. The extracellular α-DG is highly and heterogeneously glycosylated and binds with high affinity to laminins, and the transmembrane β-DG binds intracellular dystrophin. Multiple cellular functions have been proposed for DG, notwithstanding that its role in skeletal muscle...
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