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Cystic Fibrosis Mutation Detection with SPR Biosensor in Real Samples via Multiple Surfaces Binding Method.

Combinatorial chemistry & high throughput screening - 1 Jan 2017

Kayran Yasin Ugur, Ozkan-Ariksoysal Dilsat, Topkaya Seda Nur, Kaymaz Burcin Tezcanli, Can Buket Kosova

Abstract excerpt

AIM AND OBJECTIVE: Surface Plasmon Resonance (SPR) based biosensor system was developed for the detection of Delta F508 (ΔF508del) Cystic Fibrosis (CF) mutation in both synthetic and real samples. MATERIAL AND METHOD: In order to provide an effective hybridization between probe and the Polymerase Chain Reaction (PCR) amplicons (target), streptavidin was bound to the surface and biotin-tag probe was sent to the...

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Identifiers

PMID: 28049404
DOI: 10.2174/1386207320666170103154226

Genes

SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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