Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Autophagy in Hepatocytes in Infants With Alpha-1 ATD and Different Liver Disease Outcomes: A Retrospective Analysis.

Journal of pediatric gastroenterology and nutrition - 1 Jun 2017

Czarnowska Elżbieta, Bakuła Agnieszka, Bierła Joanna B, Niderla-Bielińska Justyna, Sowińska Agnieszka, Cukrowska Bożena, Cielecka-Kuszyk Joanna, Socha Piotr

Abstract excerpt

OBJECTIVES: It is unclear whether a distinct activity of pathways removing the antitrypsin (AT) protein in Alpha-1-Antitrypsin Deficiency (α1ATD) are associated with an unfavorable predisposition to liver disease in the future. The aim of this study was to determine whether liverspecific activity of AT protein disposal occurs at infancy in α1ATD with PiZZ phenotype (ATZ). METHODS: Liver samples of 17 infants with...

Topics

Autophagy
Biomarkers
Case-Control Studies
Disease Progression
Hepatocytes
Humans
Infant
Phenotype
Prognosis
Retrospective Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ubiquitin-Protein Ligases

alpha 1-Antitrypsin Deficiency

Source

Identifiers

PMID: 28045767
DOI: 10.1097/MPG.0000000000001507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy in Hepatocytes in Infants With Alpha-1 ATD and Different Liver Disease Outcomes: A Retrospective Analysis.PMID 28045767Read ↗

The Role of Autophagy in Alpha-1-Antitrypsin Deficiency: A Specific Cellular Response in Genetic Diseases Associated with Aggregation-Prone ProteinsSemantic proximity Read ↗

Liver disease in alpha-1 antitrypsin deficiency: current understanding and future therapy.Semantic proximity Read ↗

Liver disease in alpha 1-antitrypsin deficiency: a review.Semantic proximity Read ↗

Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.Semantic proximity Read ↗

Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in alpha-1-antitrypsin deficiency.Semantic proximity Read ↗

Advances in alpha-1-antitrypsin deficiency liver disease.Semantic proximity Read ↗

hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiencySemantic proximity Read ↗

Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease.Semantic proximity Read ↗

Alpha-1 antitrypsin and liver disease: mechanisms of injury and novel interventions.Semantic proximity Read ↗

Mitochondrial autophagy and injury in the liver in alpha 1-antitrypsin deficiency.Semantic proximity Read ↗

Alpha1-antitrypsin deficiency and autophagy.Semantic proximity Read ↗

Alpha-1 Antitrypsin Inclusions Sequester GRP78 in a Bile Acid-Inducible Manner.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.