Article
Association of NDRG1 gene promoter methylation with reduced NDRG1 expression in gastric cancer cells and tissue specimens.
Cell biochemistry and biophysics - 1 May 2013
Chang Xiaojing, Zhang Shuanglong, Ma Jinguo, Li Zhenhua, Zhi Yu, Chen Jing, Lu Yao, Dai Dongqiu
Abstract excerpt
NDRG1 (N-myc downstream-regulated gene 1) plays a role in cell differentiation and suppression of tumor metastasis. This study aims to determine the expression of NDRG1 mRNA and protein in gastric cancer cell lines and tissue specimens and then assess the possible cause of its aberrant expression. Six gastric cancer cell lines and 20 pairs of normal and gastric cancer tissue samples were used to assess NDRG1...
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