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Article

A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma

31 Dec 2016

Abstract excerpt

L.), has exhibited considerable preclinical activity against prostate carcinoma. Its antitumor and chemopreventive activities have been associated with diverse effects on cell cycle, apoptosis, and receptor-dependent mitogenic signaling pathways. Here we hypothesized that silibinin's pleiotropic effects may reflect its interference with epigenetic mechanisms in human prostate cancer cells. More specifically, we...

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PMID: 28042859
DOI: 10.3390/molecules22010062

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