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Article

Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers.

Scientific reports - 12 Jan 2017

Park Jung Eun, Sun Yang, Lim Sai Kiang, Tam James P, Dekker Matthijs, Chen Hong, Sze Siu Kwan

Abstract excerpt

Dietary intake of bioactive phytochemicals including the cruciferous vegetable derivative phenethyl isothiocyanate (PEITC) can reduce risk of human cancers, but possible epigenetic mechanisms of these effects are yet unknown. We therefore sought to identify the molecular basis of PEITC-mediated epigenetic tumor restriction. Colon cancer cells treated with low-dose PEITC for >1 month exhibited stable alterations...

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Identifiers

PMID: 28079155
DOI: 10.1038/srep40569
PMCID: PMC5228035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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