Article
How Does Thymine DNA Survive Ultrafast Dimerization Damage?
Molecules (Basel, Switzerland) - 31 Dec 2016
Wang Hongjuan, Chen Xuebo
Abstract excerpt
The photodimerization reaction between the two adjacent thymine bases within a single strand has been the subject of numerous studies due to its potential to induce DNA mutagenesis and possible tumorigenesis in human skin cells. It is well established that the cycloaddition photoreaction takes place on a picosecond time scale along barrierless or low barrier singlet/triplet pathways. However, the observed...
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