Article
Enabling 1536-Well High-Throughput Cell-Based Screening through the Application of Novel Centrifugal Plate Washing.
SLAS discovery : advancing life sciences R & D - 1 Jul 2017
Knight Sinead, Plant Helen, McWilliams Lisa, Murray David, Dixon-Steele Rebecca, Varghese Anet, Harper Paul, Ramne Anna, McArdle Paula, Engberg Susanna, Bennett Neil, Blackett Carolyn, Wigglesworth Mark
Abstract excerpt
Cell-based assays have long been important within hit discovery paradigms; however, improving the disease relevance of the assay system can positively affect the translation of small-molecule drug discovery, especially if adopted in the initial hit identification assay. Consequently, there is an increasing need for disease-relevant assay systems capable of running at large scale, including the use of induced...
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