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Article

Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts.

Oral oncology - 1 Jan 2017

Swick Adam D, Stein Andrew P, McCulloch Timothy M, Hartig Gregory K, Ong Irene M, Sampene Emmanuel, Prabakaran Prashanth J, Liu Cheng Z, Kimple Randall J

Abstract excerpt

BACKGROUND: Patient derived xenografts (PDXs) represent an essential tool in oncologic research, and we sought to further expand our repertoire of head and neck squamous cell carcinoma (HNSCC) while determining potential boundaries for this system. METHODS: We consented new patients for PDX development and determined if a 24-h time delay from tumor excision to xenograft implantation affected PDX establishment. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28024726
DOI: 10.1016/j.oraloncology.2016.11.017
PMCID: PMC5218527

Genes

EGFR
ERCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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