Article
Curcumin inhibits growth potential by G1 cell cycle arrest and induces apoptosis in p53-mutated COLO 320DM human colon adenocarcinoma cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2017
Dasiram Jade Dhananjay, Ganesan Ramamoorthi, Kannan Janani, Kotteeswaran Venkatesan, Sivalingam Nageswaran
Abstract excerpt
Curcumin, a natural polyphenolic compound and it is isolated from the rhizome of Curcuma longa, have been reported to possess anticancer effect against stage I and II colon cancer. However, the effect of curcumin on colon cancer at Dukes' type C metastatic stage III remains still unclear. In the present study, we have investigated the anticancer effects of curcumin on p53 mutated COLO 320DM human colon...
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