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Article

A genetic screen of the mutations in the Korean patients with early-onset Alzheimer's disease.

Clinical interventions in aging - 1 Jan 2016

An Seong Soo, Park Sun Ah, Bagyinszky Eva, Bae Sun Oh, Kim Yoon-Jeong, Im Ji Young, Park Kyung Won, Park Kee Hyung, Kim Eun-Joo, Jeong Jee Hyang, Kim Jong Hun, Han Hyun Jeong, Choi Seong Hye, Kim SangYun

Abstract excerpt

Early-onset Alzheimer's disease (EOAD) has distinct clinical characteristics in comparison to late-onset Alzheimer's disease (LOAD). The genetic contribution is suggested to be more potent in EOAD. However, the frequency of causative mutations in EOAD could be variable depending on studies. Moreover, no mutation screening study has been performed yet employing large population in Korea. Previously, we reported...

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Source

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Identifiers

PMID: 28008242
DOI: 10.2147/CIA.S116724
PMCID: PMC5167483

Genes

PSEN1
PSEN2
APOE
APP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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