Article
The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2016
D'Adamo Christopher R, Dawson Valerie J, Ryan Kathleen A, Yerges-Armstrong Laura M, Semba Richard D, Steinle Nanette I, Mitchell Braxton D, Shuldiner Alan R, McArdle Patrick F
Abstract excerpt
BACKGROUND/AIMS: Alpha-carotene is a provitamin A carotenoid present in fruits and vegetables. Higher serum concentrations of α-carotene have been associated with lower risk of cancer and all-cause mortality. Previous studies have suggested that genetic variants influence serum concentrations of provitamin A carotenoids, but to date no variants have been robustly associated with serum α-carotene concentrations....
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