Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PEAR1 gene polymorphism in a Chinese pedigree with pulmonary thromboembolism.

Medicine - 1 Dec 2016

Fu Yingyun, Sun Silong, Liang Jie, Liu Shengguo, Jiang Yiqi, Xu Lan, Mei Junpu

Abstract excerpt

To explore the correlation between platelet endothelial aggregation receptor-1 (PEAR1) genetic polymorphism and pulmonary thromboembolism (PTE).Variant loci of the PEAR1 gene were screened in a PTE pedigree, followed by verification using Sanger sequencing. These polymorphic loci were validated in 101 PTE patients and 132 matched normal patients using MassARRAY single nucleotide polymorphism (SNP) genotyping...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged, 80 and over
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oligonucleotide Array Sequence Analysis

Share to Pedigree

Share to Pulmonary Embolism

Share to Receptors, Cell Surface

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28002340
DOI: 10.1097/MD.0000000000005687
PMCID: PMC5181824

Genes

PEAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PEAR1 gene polymorphism in a Chinese pedigree with pulmonary thromboembolism.PMID 28002340Read ↗

Association between KLKB1 Polymorphisms and Pulmonary Thromboembolism.Semantic proximity Read ↗

Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.Semantic proximity Read ↗

Protein C polymorphism and susceptibility to PTE in China.Semantic proximity Read ↗

[Relationship between polymorphisms of plasminogen activator inhibitor-1 promoter gene and pulmonary thromboembolism in Chinese Han population].Semantic proximity Read ↗

[Correlation of three common variation loci in von Willebrand factor gene and pulmonary thromboembolism disease].Semantic proximity Read ↗

Genetic mutations in PEAR1 associated with cardiovascular outcomes in Chinese patients with acute coronary syndrome.Semantic proximity Read ↗

Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation.Semantic proximity Read ↗

Genetic Variants of PEAR1 are Associated with Platelet Function and Antiplatelet Drug Efficacy: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Construction and optimization of a polygenic risk model for venous thromboembolism in the Chinese population.Semantic proximity Read ↗

The genetics of venous thromboembolism: a systematic review of thrombophilia families.Semantic proximity Read ↗

Association of Genetic Variability in Selected Genes in Patients With Deep Vein Thrombosis and Platelet Hyperaggregability.Semantic proximity Read ↗

Hereditary thrombophilia in Korean patients with idiopathic pulmonary embolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.