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Article

Characterization of cytokinome landscape for clinical responses in human cancers

1 Nov 2016

Abstract excerpt

Dysfunctional intratumoral immune reactions are shaped by complex networks of cytokines (including chemokines), and how the cytokinome landscape coordinates with tumors has not been systematically investigated. Using high-dimensional datasets of cancer specimens, we explored the transcript abundance, biomarker potential, and prognostic impact of local cytokines across 19 tumor types. We found that most cytokines...

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PMID: 27999736
DOI: 10.1080/2162402x.2016.1214789

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