Article
Alternative splicing and the evolution of phenotypic novelty.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Feb 2017
Bush Stephen J, Chen Lu, Tovar-Corona Jaime M, Urrutia Araxi O
Abstract excerpt
Alternative splicing, a mechanism of post-transcriptional RNA processing whereby a single gene can encode multiple distinct transcripts, has been proposed to underlie morphological innovations in multicellular organisms. Genes with developmental functions are enriched for alternative splicing events, suggestive of a contribution of alternative splicing to developmental programmes. The role of alternative splicing...
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