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Article

The Complex Link between Apoptosis and Autophagy: a Promising New Role for RB

1 Dec 2016

Abstract excerpt

Physiological processes, as autophagy, proliferation and apoptosis are affected during carcinogenesis. Restoring cellular sensitivity to apoptotic stimuli, such as the antineoplastic cocktails, has been explored as a strategy to eliminate cancer cells. Autophagy, a physiological process of recycling organelles and macromolecules can be deviated from homeostasis to support cancer cells survival, proliferation,...

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PMID: 27991962
DOI: 10.1590/0001-3765201620160127

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