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Association of <i>HER-2</i> Copy Number and <i>HER-2/CEP-17</i> Ratio with Neoadjuvant Taxane-Containing Chemotherapy Sensitivity in Locally Advanced Breast Cancer

4 May 2012

Abstract excerpt

Abstract Learning Objectives After completing this course, the reader will be able to:Compare the clinical value of copy number–based fluorescence in situ hybridization (FISH) versus HER-2/CEP-17 ratio-based FISH in identifying patients who may benefit from taxane-containing neoadjuvant chemotherapy.Consider the implications of HER-2 copy number and aneusomy 17 when making treatment decisions in patients with...

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PMID: 22561335
DOI: 10.1634/theoncologist.2011-0381

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