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Article

The NLR protein SUMM2 senses the disruption of an immune signaling MAP kinase cascade via CRCK3.

EMBO reports - 1 Feb 2017

Zhang Zhibin, Liu Yanan, Huang Hao, Gao Minghui, Wu Di, Kong Qing, Zhang Yuelin

Abstract excerpt

MAP kinase signaling is an integral part of plant immunity. Disruption of the MEKK1-MKK1/2-MPK4 kinase cascade results in constitutive immune responses mediated by the NLR protein SUMM2, but the molecular mechanism is so far poorly characterized. Here, we report that SUMM2 monitors a substrate protein of MPK4, CALMODULIN-BINDING RECEPTOR-LIKE CYTOPLASMIC KINASE 3 (CRCK3). Similar to SUMM2, CRCK3 was isolated from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27986791
DOI: 10.15252/embr.201642704
PMCID: PMC5286374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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