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Arabidopsis PP2C clade B members are negative feedback regulators of MPK3/MPK6 MAPK cascade in plant immunity and development.

Plant physiology - 2 Jul 2026

Qiu Qin, Li Bixin, Ma Panpan, Wang Shiyuan, Ma Xuying, Tang Xiaofei, Zhang Shuqun, Zhang Mengmeng

Abstract excerpt

MAPK activation is a key event downstream of receptor-mediated signaling in plant immunity and development. While the activation of MAPK cascades is well-studied, their negative regulatory mechanisms remain less understood. Expression profiling of conditional gain-of-function MPK3/MPK6 plants identified the induction of clade B phosphatase genes from the PP2C family, known as AP2Cs. Overexpression of any of the 4...

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PMID: 42378655
DOI: 10.1093/plphys/kiag458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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