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Article

Arabidopsis E3 ligase KEG associates with and ubiquitinates MKK4 and MKK5 to regulate plant immunity.

Journal of integrative plant biology - 1 Feb 2021

Gao Chenyang, Sun Pengwei, Wang Wei, Tang Dingzhong

Abstract excerpt

Mitogen-activated protein kinase (MAPK) cascades are highly conserved signaling modules that regulate plant immune responses. The Arabidopsis thaliana Raf-like MAPK kinase kinase ENHANCED DISEASE RESISTANCE1 (EDR1) is a key negative regulator of plant immunity that affects the protein levels of MKK4 and MKK5, two important MAPK cascade members, but the underlying mechanism is poorly understood. Here, genome-wide...

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PMID: 32877006
DOI: 10.1111/jipb.13007

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