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Article

CAMTA3 repressor destabilization triggers TIR domain protein TN2-mediated autoimmunity in the Arabidopsis exo70B1 mutant.

The Plant cell - 1 May 2024

Liu Na, Jiang Xiyuan, Zhong Guitao, Wang Wei, Hake Katharina, Matschi Susanne, Lederer Sarah, Hoehenwarter Wolfgang, Sun Qianqian, Lee Justin, Romeis Tina, Tang Dingzhong

Abstract excerpt

Calcium-dependent protein kinases (CPKs) can decode and translate intracellular calcium signals to induce plant immunity. Mutation of the exocyst subunit gene EXO70B1 causes autoimmunity that depends on CPK5 and the Toll/interleukin-1 receptor (TIR) domain resistance protein TIR-NBS2 (TN2), where direct interaction with TN2 stabilizes CPK5 kinase activity. However, how the CPK5-TN2 interaction initiates...

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PMID: 38309956
DOI: 10.1093/plcell/koae036
PMCID: PMC11062451

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