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Article

Within-Host Evolution of Simian Arteriviruses in Crab-Eating Macaques.

Journal of virology - 15 Feb 2017

Moncla Louise H, Weiler Andrea M, Barry Gabrielle, Weinfurter Jason T, Dinis Jorge M, Charlier Olivia, Lauck Michael, Bailey Adam L, Wahl-Jensen Victoria, Nelson Chase W, Johnson Joshua C, Caì Yíngyún, Goldberg Tony L, O'Connor David H, Jahrling Peter B, Kuhn Jens H, Friedrich Thomas C

Abstract excerpt

Simian arteriviruses are a diverse clade of viruses infecting captive and wild nonhuman primates. We recently reported that Kibale red colobus virus 1 (KRCV-1) causes a mild and self-limiting disease in experimentally infected crab-eating macaques, while simian hemorrhagic fever virus (SHFV) causes lethal viral hemorrhagic fever. Here we characterize how these viruses evolved during replication in cell culture...

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Identifiers

PMID: 27974564
DOI: 10.1128/JVI.02231-16
PMCID: PMC5286893

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