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Article

DNA methylation is an independent prognostic marker of survival in adrenocortical cancer

14 Dec 2016

Abstract excerpt

CONTEXT: Adrenocortical cancer (ACC) is an aggressive tumor with a heterogeneous outcome. Prognostic stratification is difficult even based on tumor stage and Ki67. Recently integrated genomics studies have demonstrated that CpG islands hypermethylation is correlated with poor survival. OBJECTIVE: The goal of this study was to confirm the prognostic value of CpG islands methylation on an independent cohort....

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PMID: 27967600
DOI: 10.1210/jc.2016-3205

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