Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression and production of cardiac angiogenic mediators depend on the Trypanosoma cruzi-genetic population in experimental C57BL/6 mice infection.

Microvascular research - 1 Mar 2017

Shrestha Deena, Bajracharya Bijay, Paula-Costa Guilherme, Salles Beatriz C, Leite Ana Luísa J, Menezes Ana Paula J, Souza Débora Ms, Oliveira Laser Am, Talvani André

Abstract excerpt

Mammalian cardiac cells are important targets to the protozoan Trypanosoma cruzi. The inflammatory reaction in the host aims at eliminating this parasite, can lead to cell destruction, fibrosis and hypoxia. Local hypoxia is well-defined stimulus to the production of angiogenesis mediators. Assuming that different genetic T. cruzi populations induce distinct inflammation and disease patterns, the current study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenic Proteins
Share to Chagas Cardiomyopathy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Inflammation Mediators

Share to Mice, Inbred C57BL

Share to Myocardium

Share to Neovascularization, Physiologic

Share to Trypanosoma cruzi

Source

Identifiers

PMID: 27956355
DOI: 10.1016/j.mvr.2016.12.002

Genes

CCL5
TNF
CCL2
CCL3
CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression and production of cardiac angiogenic mediators depend on the Trypanosoma cruzi-genetic population in experimental C57BL/6 mice infection.PMID 27956355Read ↗

Phenotypic, functional and serological aspects of genotypic-specific immune response of experimental T. cruzi infection.Semantic proximity Read ↗

Differential modulation of mouse heart gene expression by infection with two <i>Trypanosoma cruzi</i> strains: a transcriptome analysisSemantic proximity Read ↗

BALB/c and C57BL/6 Mice Cytokine Responses to Trypanosoma cruzi Infection Are Independent of Parasite Strain InfectivitySemantic proximity Read ↗

MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological OutcomesSemantic proximity Read ↗

Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human–host interactionsSemantic proximity Read ↗

Correlation of blood-based immune molecules with cardiac gene expression profiles reveals insights into Chagas cardiomyopathy pathogenesisSemantic proximity Read ↗

Different genotypes of Trypanosoma cruzi produce distinctive placental environment genetic response in chronic experimental infection.Semantic proximity Read ↗

Comparative Transcriptome Profiling of Human Foreskin Fibroblasts Infected with the Sylvio and Y Strains of Trypanosoma cruziSemantic proximity Read ↗

Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruziSemantic proximity Read ↗

Virulence of Trypanosoma cruzi Strains Is Related to the Differential Expression of Innate Immune Receptors in the HeartSemantic proximity Read ↗

Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.Semantic proximity Read ↗

Comparative study of the biological properties of Trypanosoma cruzi I genotypes in a murine experimental model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.