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Article

Personalized Drug Dosage - Closing the Loop.

Pharmaceutical research - 1 Aug 2017

Tucker Geoffrey T

Abstract excerpt

A brief account is given of various approaches to the individualization of drug dosage, including the use of pharmacodynamic markers, therapeutic monitoring of plasma drug concentrations, genotyping, computer-guided dosage using 'dashboards', and automatic closed-loop control of pharmacological action. The potential for linking the real patient to his or her 'virtual twin' through the application of...

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Share to Biomarkers, Pharmacological
Share to Dose-Response Relationship, Drug
Share to Drug Dosage Calculations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27943015
DOI: 10.1007/s11095-016-2076-0
PMCID: PMC5498646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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