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Article

Dynamic pharmacogenetic models in anticoagulation therapy.

Clinics in laboratory medicine - 1 Dec 2008

Bon Homme Marjorie, Reynolds Kristen K, Valdes Roland, Linder Mark W

Abstract excerpt

This article demonstrates how a dynamic clinical-support tool can guide individualized drug therapy. We use the drug warfarin as a model to demonstrate how pharmacogenetics when combined with fundamental principles of pharmacokinetic and pharmacodynamics can provide a powerful decision-support tool to optimize personalized therapeutics.

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Share to Anticoagulants
Share to Cytochrome P-450 CYP2C9
Share to Decision Support Systems, Clinical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mixed Function Oxygenases

Share to Models, Theoretical

Share to Vitamin K Epoxide Reductases

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Source

Identifiers

PMID: 19059061
DOI: 10.1016/j.cll.2008.10.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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